G-418, Selective antibiotic
The G418 sulfate is an aminoglycoside antibiotic identical to gentamicin B1 produced by Micromonospora rhodorangea. It blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. It is used to select and maintain eukaryotic cells expressing the neo gene (neomycin). The quality and purity of the G-418 is essential to achieve good and consistent selection.
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G-418 Sulfate:
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Chemical Name: (2R,3S,4R,5R,6S)-5-amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylaminooxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-2-(1-hydroxyethyl)oxane-3,4-diol
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Molecular Formula: C20H40N4O10 . 2H2SO4
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Molecular weight: 692.71 g/mol
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| GS21000 | G-418, sulfate |
Price: Login | | | 1g
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MSDS G418