Pro-DeliverIN^™

Protein delivery reagent Pro-DeliverIN™ is an innovative reagent allowing intracellular delivery of biologically active proteins. This lipid-based formulation is the first serum compatible reagent to deliver functional proteins into living cells. Consequently, it is the only reagent which allows livering protein in vitro and in vivo.

Due to its specific properties, it is able to capture proteins through electrostatic and hydrophobic interactions. Consequently, there are no needs of covalent linking (chemical or genetic). Pro-DeliverIN™ allows studying specific protein function, protein localization, enlightening new molecular mechanisms...

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• Functionally active protein delivery

• Highly efficient in many primary cells and cell lines

• Serum compatible

• Biodegradable and no cytotoxicity

• Easy: straightforward protocol and ready-to-use
  
  

Delivery of functionally active protein

Pro-DeliverIN™ permits the delivery of a functional protein, making possible the study of complex molecular mechanisms such as apoptosis,cell division …

Apoptosis and cell death induction in cell lines

Highly efficient protein transfection

Proteins are efficiently delivered in the cytoplasmof a large number of living cells. For example, several different proteins such as Phycoerythrin (a very large bacterial fluorescentprotein), Serum Albumin, ß-Galactosidase, Caspase, can be transported inside cells.

Delivery of various proteins in different cell lines

Non toxic and serum compatible protein delivery reagent

Pro-DeliverIN™ is fully biodegradable and does not interfere with cellular mechanisms. In addition, it is compatible with serum containing culture media. You can obtain a significant amount of proteins transported with no medium change which is less stressful for your cells.

Delivery of proteins inside cells in presence of serum

Rapid and easy-to-use protein transfection reagent

1- Mix Pro-DeliverIN™ and proteins
2- Incubate 10 min at room temperature
3- Add onto cells and incubate under standard conditions

Each kit contains 10 µg of R-phycoerythrin at a concentration of 100 µg / mL in PBS.