SelfMag kits, based on MagnetoFection™ Technology, allow creating your own magnetic delivery system. These kits have been designed to couple your molecules of interest onto magnetic nanoparticles and to deliver them into cells by magnetic targeting. They can be used either for transporting proteins, peptides, oligonucleotides, drugs, or any other molecules into living cells, or for targeting specific cells.
The molecule of interest is covalently coupled by using the surface
reactive COOH or NH2 groups of the magnetic nanoparticles. The
resulting coupled magnetic nanoparticles are delivered intracellularly
with a unique MagFectin reagent.
Two kits are proposed:
- SelfMag Carboxy Kit which contains COOH reactive groups
- Selfmag Amino Kit which contains NH2 reactive groups
These kits have been successfully tested to deliver different types of molecules inside cells.
Suitable for the delivery of numerous molecules
Mono dispersed and size-controlled magnetic nanoparticles
Ready to use coupling, washing and storage buffers
Highly efficient MagFectin delivery reagent
Easy handling and fast results
Comprehensive and detailed protocol
Efficient coupling of biomolecules on SelfMag magnetic nanoparticles
SelfMag Carboxy Kit
SelfMag Amino Kit
High delivery efficiency mediated by MagFectin reagent
Delivery in several cell types
Efficiently intracellular delivery of molecules coupled to magnetic nanoparticles is achieved upon an appropriate magnetic field without any toxicity.
Quantity of molecules effectively delivered inside cells
ß-galactosidase delivery with SelfMag Carboxy Kit
No Toxicity
NIH3T3 cells growth during the delivery assay
Rapid and easy-to-use enhancer transfection reagent
1. Mix nanoparticles with your molecule of interest
2. Add the coupling reagent
3. Incubate at room temperature
4. Wash the coupled nanoparticles
5. Deliver the particles into cells with MagFectin
SelfMag Amino and Carboxy Kit composition
1. Magnetic nanoparticles (1 mL)
2. Coupling, washing / storage buffer and EDC
3. MagID: magnetic device for buffer exchange and washing procedures
4. MagFectin: magnetic nanoparticles delivery reagent
5. Super Magnetic Plate : specific magnetic field for intracellular delivery