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Small-Molecule-Mediated Depletion of the DYRK1B Protein Scaffold
Authors: Miriam Ems, et al. Source: ACS Pharmacol. Transl. Sci. They identified LCTB-92, a small molecule from the leucettinib class of DYRK inhibitors... -
LNP-mediated mRNA delivery in human PBMC: T cell-targeted transfection
Application note: transfection efficiency, cell-type tropism and viability of a new ionizable lipid LNP formulation in human PBMCs, with focus on T cells. -
Geneformer-guided multiomics identifies Pbx1 as a network hub of HSC aging
Authors: Hiroshi Kobayashi et al. Source: Science Advances. They integrated deep learning foundation models with transcriptomic and epigenetic profiling to...






